Glioblastoma, also known as glioblastoma multiforme, is a common, aggressive, and fast-growing brain tumor that begins in the cells called astrocytes that support nerve function. The tumor occurs when these cells start to grow out of control abnormally, and they can invade nearby brain tissues. A few decades back, people with glioblastoma tended to live a few weeks or weeks after diagnosis. With advancements in the medical field, physicians are now trying to prolong the life of patients with glioblastoma.

This cancer can occur in people of any age but is most commonly seen in adults aged 45 to 70. More than women, men are at slightly increased risk. Research has found some factors that increase the risk of developing glioblastoma. Those risk factors include exposure to chemicals – synthetic rubber, petroleum, pesticides, & vinyl chloride, having genetic conditions such as Li-Fraumeni syndrome, neurofibromatosis, and previous radiation therapy to the head.

Since the growing tumor pressures the brain, patients experience symptoms quickly. The symptoms include loss of appetite, nausea, vomiting, seizures, speech problems, memory problems, double or blurred vision, headaches, personality changes, muscle weakness, numbness, or tingling sensation. If your physician suspects a brain tumor, they might perform a neurological exam, imaging tests (MRI, PET, & CT), and biopsy to diagnose the glioblastoma.

In a neurological exam, the physician will ask about the symptoms and signs and examine the vision, reflexes, balance, and coordination. Imaging tests will provide information about the size and location of the tumors. The cancer cells will be collected and examined in the laboratory in a biopsy. It will help the health care provider plan treatment and understand the prognosis. Unfortunately, the cure is not possible with glioblastoma as it is aggressive cancer, and about 7 percent of people diagnosed with glioblastoma can live for five years. Treatment available can help minimize the symptoms and improve the quality of life.

We have a medication that is used in treatment of glioblastoma multiforme in combination with radiotherapy. This medication contains the active ingredient Temozolomide which works by following a process known as alkylation. Once administered, this medication gets converted into its active form metabolite 5-(3-methyltriazen-1-yl) imidazole-4-carboxamide (MTIC), which reacts with water to form methyl diazonium ions. The methyl group from the methyl diazonium ions moves into the DNA and break its strands resulting in cell cycle arrest and death. If you have glioblastoma multiforme, then your doctor might prescribe you Temoside 100mg Capsule.