Menopause is defined as an event of aging, that marks the end of the occurrence of the menstrual cycle in women. Menopause is confirmed only when a woman has not gone through her menstrual period for a period of 12 months.  Hence, it denotes the end of female reproductive years and is understood by the term that women lacks the potential to become pregnant after menopause. The ideal age of menopause in women is the around late 40s to early 50s.

While menopause is a natural occurrence in women. In other ways, menopause is stated as the time during which the ovaries and female reproductive organs fail to produce eggs for fertilization. Besides this function ovaries are also involved in the synthesis of hormones.  The entire menstruation process is regulated by the female reproductive hormone namely estrogen and progesterone which are secreted by the ovaries. In women, as a part of natural aging, the functions of the ovaries tend to impair over the period and cause dysregulation in the levels of these female hormones.  

Estrogen is the hormone that plays a major role in fat metabolism in women by controlling blood cholesterol levels. After menopause, due to the impairment of the ovaries to make estrogen, only the fat tissues begin to produce estrogen. Hence, women who are overweight can develop elevated levels of estrogen. A few studies state that women being overweight or obese are at greater risk of getting breast cancer due to high levels of reproductive hormones involved in tumor growth.

Besides causing cancer, obesity after menopause can cause a spike in insulin production related to increasing the risk of many other cancers. It has been proclaimed that women being obese before menopause are at risk of developing triple-negative breast cancer whereas women gaining weight post menopause are associated with a strong risk of hormone-positive breast cancer. Breast cancer is classified based on the hormone status to decide upon the treatment plan.

The hormone status of breast cancer is identified after performing a biopsy of the tumor. The hormone-positive breast cancer is fast-growing breast cancer that rapidly spreads to the neighboring organs. Hormone-positive breast cancer denotes that the breast cancer cells can either have estrogen or progesterone receptors. The treatment involved in hormone-positive breast cancer involves hormonal therapy that aims to reduce estrogen levels. 

It is found that women with estrogen-positive breast cancer present with a better treatment outlook within a short duration. However, this type of breast cancer can reoccur many years after the treatment. Letrozole is one such drug that is involved in hormonal therapy. It works by blocking the aromatase, an enzyme that plays a role in the overproduction of estrogen. Since the high amounts of the hormone fuel the growth of breast cancer, this drug reduces the high expression of the hormones ad retards the tumor development. 

Femara 2.5mg Tablet is one such product that contains letrozole as the active constituent. It is intended for its use in any stage of breast cancer i.e it can either be used before or after surgery and can be used along with other hormonal therapy agents. Femara 2.5 Tablet also aims to prevent breast cancer recurrence by keeping the estrogen levels under control. Femara 2.5 mg Tabet is advised for only postmenopausal women and it is not recommended for pregnant or breastfeeding women as it can harm the baby. Incase, if you are a women of childbearing age, it is better to discuss with your doctor before starting the treatment.